Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8277012 | Journal of the Neurological Sciences | 2014 | 7 Pages |
Abstract
In FRDA, aberrant glucose metabolism is linked to increasing age, longer GAA repeat length on the shorter allele, frataxin point mutations, and increasing BMI. The effect of age to some degree may be mediated through changes in BMI, with increasing age associated with increases in BMI, and with HOMA-IR and insulin increases in children.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Nathaniel R. Greeley, Sean Regner, Steve Willi, David R. Lynch,