| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8280510 | Journal of the Neurological Sciences | 2012 | 7 Pages |
Abstract
These findings demonstrate distinctive effects of cilostazol and other PDE inhibitors on HBECs, including enhanced barrier characteristics and mitigation of response to histamine. PKA-mediated effects of cilostazol were prominent in this model. These in vitro findings are consistent with therapeutic potential of PDE inhibitors in human brain microvascular disorders.
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Authors
Shuo Liu, Chuanhui Yu, Fan Yang, Annlia Paganini-Hill, Mark J. Fisher,