| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8281174 | Journal of the Neurological Sciences | 2012 | 4 Pages |
Abstract
The GSTM1 enzyme detoxifies substances such as exogenous and endogenous metabolites and plays a regulatory role in cellular signaling. Previous studies have highlighted that GSTM1 has a role in neurodegenerative disorders, but no data have associated the GSTM1 gene with AD risk. Our outcome suggests that the GSTM1 null genotype is a risk factor for AD in Italian patients.
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Authors
Sara Piacentini, Renato Polimanti, Rosanna Squitti, Mariacarla Ventriglia, Emanuele Cassetta, Fabrizio Vernieri, Paolo Maria Rossini, Dario Manfellotto, Maria Fuciarelli,