| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8281648 | Journal of the Neurological Sciences | 2012 | 5 Pages |
Abstract
Clinical findings of decreased visual acuity, gaze impersistence, voluntary upgaze restriction, eyelid opening apraxia, and saccadic horizontal smooth pursuits are more frequent in patients with ALS than in similar-aged controls. These findings are potential clinical markers of neurodegeneration beyond upper and lower motor neuron disease in ALS. Further study is warranted regarding their application to disease categorization and outcomes assessment.
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Authors
Heather E. Moss, Leo McCluskey, Lauren Elman, Katelin Hoskins, Lauren Talman, Murray Grossman, Laura J. Balcer, Steven L. Galetta, Grant T. Liu,