Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8281710 | Journal of the Neurological Sciences | 2012 | 8 Pages |
Abstract
HDLS is an under-recognized disease and in reporting these cases, we aim to increase the awareness of the disorder. Due to varied and wide phenotypic presentations, which may imitate several neurodegenerative diseases, HDLS can be difficult to diagnose. Definitive diagnosis can be established only by direct brain tissue examination. Familiarity with the clinical presentation and typical neuroimaging findings may be helpful in narrowing the diagnosis.
Keywords
HDLSCADASILNMOPSPACETPHAVDRLcerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathyAutosomal DominantDepressionAlzheimer's diseaseWhite matter diseaseParkinson diseasePositron emission tomographyNeuromyelitis opticaProgressive supranuclear palsyCSFCerebrospinal fluidMultiple sclerosishuman immunodeficiency virusHIVParkinsonismPET
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Authors
Christina Sundal, Jennifer Lash, Jan Aasly, Sarka Ãygarden, Sigrun Roeber, Hans Kretzschman, James Y. Garbern, Alex Tselis, Rosa Rademakers, Dennis W. Dickson, Daniel Broderick, Zbigniew K. Wszolek,