Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8282260 | Journal of the Neurological Sciences | 2011 | 8 Pages |
Abstract
In patients with rapidly progressive cognitive decline with negative workup for common etiologies, there should be a high index of suspicion for WD. Diagnosis of WD remains a challenge as traditional methods commonly fail to culture T. whipplei. PET scans can help in identifying areas of inflammation that can be biopsied. Our case proves that a negative serum and CSF PCR should not exclude CNS WD and a brain biopsy of the lesion with PCR assay should be performed when possible.
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Authors
Wazim Mohamed, Erin Neil, William J. Kupsky, Csaba Juhász, Sandeep Mittal, Sunitha Santhakumar,