Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8282528 | Journal of the Neurological Sciences | 2011 | 7 Pages |
Abstract
Large changes of the in vivo Nf stoichiometry have only little effect on the simulated structure of Nf sidearms independent of phosphorylation and ionic strength. This suggests that the axonal cytoskeleton is remarkably stable, possibly relying on NfL which forms a dense brush around the Nf backbone and virtually excludes NfM and NfH from the core region, such that the dropout of NfM and NfH can be dealt with structurally.
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Authors
Seonghoon Kim, Rakwoo Chang, Charlotte Teunissen, Yeshitila Gebremichael, Axel Petzold,