Article ID Journal Published Year Pages File Type
8285014 Mechanisms of Ageing and Development 2013 8 Pages PDF
Abstract
► Aim to study the role of rare functional variants in human longevity. ► Implementation of target capture and next-generation sequencing. ► Comprehensive analysis of 988 candidate genes for discovery of novel nsSNPs. ► Identification of GABRR3 and PMS2 as potential longevity-associated genes.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
Discovery of novel non-synonymous SNP variants in 988 candidate genes from 6 centenarians by target capture and next-generation sequencing
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