| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8285146 | Mechanisms of Ageing and Development | 2012 | 4 Pages |
Abstract
⺠We raise concerns about a previously published study proposing that the C. elegans ELT-3 GATA factor controls intestinally expressed aging-associated genes. ⺠We find that ELT-3 is not significantly expressed in the adult C. elegans intestine. ⺠Contrary to the previously published study, we find that an elt-3 loss-of-function mutation (deletion of the zinc finger DNA binding domain) does not revert the extended lifespan of a daf-2(e1370) mutation.
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Related Topics
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Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Tabitha Tonsaker, Ryan M. Pratt, James D. McGhee,