Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8285172 | Mechanisms of Ageing and Development | 2011 | 8 Pages |
Abstract
⺠Mild-intensity exercise induced muscular adaptations in aging rats. ⺠Mild-intensity exercise improved age-related learning and memory impairments. ⺠Exercise increased hippocampal plasticity via the activation of AKT, CREB and BDNF. ⺠Short bouts of mild exercise counteract brain function decline in aged rats.
Keywords
PI3-Kcyclic-AMP response element binding proteinEXEMLSSCREBLTMSTMBDNFMAPKAktlong-term potentiationLTPlong-term memoryshort-term memoryCNSAgingcentral nervous systemBrain-derived neurotrophic factorPhosphatidylinositol 3-kinasephysical exerciseSedentaryHippocampussedmitogen-activated protein kinaseSerine/threonine protein kinaseSynaptic plasticityglutamateLearning and memory
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Aderbal S. Jr., Adalberto A. Castro, Eduardo L. Moreira, Viviane Glaser, Adair R.S. Santos, Carla I. Tasca, Alexandra Latini, Rui D.S. Prediger,