Article ID Journal Published Year Pages File Type
8285264 Mechanisms of Ageing and Development 2011 12 Pages PDF
Abstract
► The changes of the NDI value was insignificant during aging. ► Apoptotic cell level was increased during aging. ► Old horse lymphocytes were more prone to oxidative DNA damage, sister chromatid exchange and bleomycin-induced chromatid breaks. ► Micronuclei formation was dropped during aging which was strongly correlated with elevated occurrence of apoptosis within old groups. ► Age-associated changes in genomic stability may contribute to progress of aging process in the horse.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
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