Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8285286 | Mechanisms of Ageing and Development | 2011 | 7 Pages |
Abstract
⺠Maternal protein restriction leads to transgenerational changes in the pancreas. ⺠It delays islet maturation and reduces the number of islets in F1. ⺠It reduces beta cell mass and causes hypoinsulinemia in F1-F3 offspring. ⺠Offspring have lower pancreatic islets and altered distribution of alpha/beta cells.
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Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Eliete Dalla Corte Frantz, Marcia Barbosa Aguila, Alessandra da Rocha Pinheiro-Mulder, Carlos Alberto Mandarim-de-Lacerda,