Article ID Journal Published Year Pages File Type
8285286 Mechanisms of Ageing and Development 2011 7 Pages PDF
Abstract
► Maternal protein restriction leads to transgenerational changes in the pancreas. ► It delays islet maturation and reduces the number of islets in F1. ► It reduces beta cell mass and causes hypoinsulinemia in F1-F3 offspring. ► Offspring have lower pancreatic islets and altered distribution of alpha/beta cells.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
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