Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8285423 | Parkinsonism & Related Disorders | 2018 | 4 Pages |
Abstract
A 3-point change is the minimal clinically important change after treatment using TWSTRS as endpoint with higher cutoffs for greater baseline disease severity. For an average trial population (TWSTRS-total: 40-45), a 12-point decrease is clinically meaningful.
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Authors
Alberto J. Espay, Richard Trosch, Gustavo Suarez, Jonathan Johnson, Dominic Marchese, Cynthia Comella,