Hippocampal neurons require a large pool of glutathione to sustain dendrite integrity and cognitive function

Article ID	Journal	Published Year	Pages	File Type
8286255	Redox Biology	2018	10 Pages	PDF

Keywords

DTNB Tuj1 MAP2 CA3 MEFs GCL GSSG GSH in vivo knockdown shRNA CA1 DMEM SDS FBS 4-Hydroxy-tamoxifen 5,5′-dithio-bis-(2-nitrobenzoic acid)DMSO Dulbecco's modified Eagle's medium small hairpin RNA ROS cornu ammonis area 1 Memory impairment Cornu Ammonis area 3 Dimethylsulfoxide sodium dodecyl sulfate fetal bovine serum glutamate-cysteine ligase glutamate-cysteine ligase, catalytic subunit mouse embryonic fibroblasts Neurons polymerase chain reaction PCR microtubule-associated protein-2 Glutathione glutathione, oxidized form glutathione, reduced form Reactive oxygen species

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Hippocampal neurons require a large pool of glutathione to sustain dendrite integrity and cognitive function

Authors

Seila Fernandez-Fernandez, Veronica Bobo-Jimenez, Raquel Requejo-Aguilar, Silvia Gonzalez-Fernandez, Monica Resch, Monica Carabias-Carrasco, Joaquim Ros, Angeles Almeida, Juan P. Bolaños,