Nicotinamide riboside attenuates alcohol induced liver injuries via activation of SirT1/PGC-1Î±/mitochondrial biosynthesis pathway

Article ID	Journal	Published Year	Pages	File Type
8286404	Redox Biology	2018	10 Pages	PDF

Keywords

CYP2E1 T2D PGC-1α NAMPT NRF-1 NMN TFAM UCP2 sirtuin 1 Sirt3 ALDH PPAR-α NRF-2 CPT-1α Sirtuin 3 NRK PDHc Mitochondrial biosynthesis peroxisome proliferator-activated receptor γ coactivator-1α Sirt1 PPAR-γ ADH SDH NAD+Nmnat ROS ALD aldehyde dehydrogenase fatty acid synthase Alcohol dehydrogenase alcoholic liver disease Oxidative stress Type 2 diabetes Nicotinamide riboside succinate dehydrogenase Citrate synthase cytochrome P450 2E1 Nuclear respiratory factor 1 nuclear respiratory factor 2 Fasn Uncoupling Protein-2 calorie restriction NAM nicotinamide adenine dinucleotide nicotinamide phosphoribosyl transferase nicotinamide mononucleotide Nicotinamide pyruvate dehydrogenase complex TCA cycle tricarboxylic acid cycle Reactive oxygen species peroxisome proliferator-activated receptor γ

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Ageing

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Nicotinamide riboside attenuates alcohol induced liver injuries via activation of SirT1/PGC-1Î±/mitochondrial biosynthesis pathway

Authors

Sufan Wang, Ting Wan, Mingtong Ye, Yun Qiu, Lei Pei, Rui Jiang, Nengzhi Pang, Yuanling Huang, Baoxia Liang, Wenhua Ling, Xiaojun Lin, Zhenfeng Zhang, Lili Yang,