Synergistic interaction of fatty acids and oxysterols impairs mitochondrial function and limits liver adaptation during nafld progression

Article ID	Journal	Published Year	Pages	File Type
8286546	Redox Biology	2018	11 Pages	PDF

Keywords

5α MMP NAFLD FFAs UCP2 TNF TFAM 7KC BN-PAGE NAFL CTRL Cytochromes P450 PGC1α 6-oxo-cholestan-3β,5α-diol 7-Ketocholesterol 7β-hydroxycholesterol CYPs Mitochondrial DNA Δψ Non-alcoholic steatohepatitis Oleic acid Fatty acids Free fatty acids standard deviation of the mean Oxysterols non-alcoholic fatty liver disease analysis of variance ANOVA mtDNA Triol tumor necrosis factor SDM Mitochondria Nash Palmitic acid Mitochondrial membrane potential uncoupling protein 2 high-fat threshold cycle Non-alcoholic fatty liver Control

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Ageing

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Synergistic interaction of fatty acids and oxysterols impairs mitochondrial function and limits liver adaptation during nafld progression

Authors

Francesco Bellanti, Rosanna Villani, Rosanna Tamborra, Maria Blonda, Giuseppina Iannelli, Giorgia di Bello, Antonio Facciorusso, Giuseppe Poli, Luigi Iuliano, Carlo Avolio, Gianluigi Vendemiale, Gaetano Serviddio,