Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription

Article ID	Journal	Published Year	Pages	File Type
8286640	Redox Biology	2018	13 Pages	PDF

Keywords

GCLC NF-κB MSR IκK Nrf2 VSMC GSH TRAF6 CaMKII GSSG SQSTM1 Ca2+/Calmodulin-dependent kinase II ROS Autophagy Vascular smooth muscle cells smooth muscle antioxidant response element TNF receptor associated factor 6 nuclear factor (erythroid-derived 2)-like 2 nuclear factor kappa-light-chain-enhancer of activated B cells Keap-1 glutamate-cysteine ligase Methionine methionine sulfoxide reductase inhibitor of nuclear factor kappa-B kinase ARE Kelch-like ECH-associated protein 1 reduced glutathione oxidized glutathione glutathione reductase Reactive oxygen species ubiquitination

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Ageing

Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription

Authors

Steven M. Pennington, Paula R. Klutho, Litao Xie, Kim Broadhurst, Olha M. Koval, Michael L. McCormick, Douglas R. Spitz, Isabella M. Grumbach,