Identification of novel Nrf2 activators from Cinnamomum chartophyllum H.W. Li and their potential application of preventing oxidative insults in human lung epithelial cells

Article ID	Journal	Published Year	Pages	File Type
8286776	Redox Biology	2018	27 Pages	PDF

Keywords

NQO1 RNS DAPI CHX Heme oxygenase-1 PPI HO-1 GST Nrf2 NLD THD γ-GCS NAD(P)H: quinone oxidoreductase Nrf2 activator NAD(P)H: quinone reductase 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide 6-diamidino-2-phenylindole keap1 MTT ROS γ-glutamylcysteine synthetase Sodium arsenite Arsenic Acridine orange ethidium bromide COPD Chronic obstructive pulmonary disease Protein–protein interaction Sulforaphane cycloheximide antioxidant response element nuclear factor erythroid 2-related factor 2 ARE As(III)Kelch-like ECH-associated protein 1 Column chromatography glutathione S-transferase reactive nitrogen species Reactive oxygen species

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Identification of novel Nrf2 activators from Cinnamomum chartophyllum H.W. Li and their potential application of preventing oxidative insults in human lung epithelial cells

Authors

Ming-Xing Zhou, Guo-Hui Li, Bin Sun, You-Wei Xu, Ai-Ling Li, Yan-Ru Li, Dong-Mei Ren, Xiao-Ning Wang, Xue-Sen Wen, Hong-Xiang Lou, Tao Shen,