Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity

Article ID	Journal	Published Year	Pages	File Type
8287060	Redox Biology	2017	12 Pages	PDF

Keywords

FTC RITC ZO-1 PECAM-1 NQO-1 TEER Trans-endothelial electrical resistance SFN ICAM-1 HO-1 Nrf2 FITC CSE ROS Tight junction tight junctions ISO COPD Chronic obstructive pulmonary disease Oxidative stress Glucose transporter Cigarette smoke Type 2 diabetes mellitus Rhodamine B isothiocyanate International Organization for Standardization BBB blood brain barrier Sulforaphane Tobacco smoke nuclear factor erythroid 2-related factor cigarette smoke extract anti-oxidant response element fluorescein isothiocyanate Blood-brain barrier Metformin intercellular adhesion molecule-1 platelet endothelial cell adhesion molecule-1 Hyperglycemia ARE heme oxygenase 1 Reactive oxygen species

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Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity

Authors

Shikha Prasad, Ravi K. Sajja, Mohammad Abul Kaisar, Jee Hyun Park, Heidi Villalba, Taylor Liles, Thomas Abbruscato, Luca Cucullo,