A pharma-wide approach to address the genotoxicity prediction of primary aromatic amines

Article ID	Journal	Published Year	Pages	File Type
8376676	Computational Toxicology	2018	9 Pages	PDF

Keywords

ATR PAAS FNR GLP SPEC FPR OECD 2AA KNIME (Q)SAR SENS Primary aromatic amines Expert review Ames test Good Laboratory Practice Mutagenicity Sensitivity Balanced accuracy Quantitative structure-activity relationship SMARTS Organisation for Economic Co-operation and Development true positive false positive false negative true negative False positive rate False negative rate Specificity

Related Topics

Physical Sciences and Engineering Mathematics Computational Mathematics

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A pharma-wide approach to address the genotoxicity prediction of primary aromatic amines

Authors

Mukesh Patel, Michael Kranz, Jordi Munoz-Muriedas, James S. Harvey, Amanda Giddings, Steve Swallow, Mick Fellows, Russell Naven, Anne-Laure Werner, David J. Yeo, Frank Bringezu, Joerg Wichard, Andreas Sutter, Susanne Glowienke, Lewis Whitehead,