Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8385433 | International Journal of Medical Microbiology | 2014 | 12 Pages |
Abstract
When E. coli subtype definition included ESBL types, phylogenetic grouping and antimicrobial susceptibility data, the proportion of isolates allocated to common clusters was markedly reduced. Nevertheless, relevant proportions of same subtypes were detected in isolates from the human and livestock and companion animal populations included in this study, suggesting exchange of bacteria or bacterial genes between these populations or a common reservoir. In addition, these results clearly showed that there is some similarity between ESBL genes, and bacterial properties in isolates from the different populations. Finally, our current approach provides good insight into common and population-specific clusters, which can be used as a basis for the selection of ESBL-producing isolates from interesting clusters for further detailed characterizations, e.g. by whole genome sequencing.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry, Genetics and Molecular Biology (General)
Authors
Lars Valentin, Hannah Sharp, Katja Hille, Uwe Seibt, Jennie Fischer, Yvonne Pfeifer, Geovana Brenner Michael, Silke Nickel, Judith Schmiedel, Linda Falgenhauer, Anika Friese, Rolf Bauerfeind, Uwe Roesler, Can Imirzalioglu, Trinad Chakraborty,