Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8385901 | International Journal of Medical Microbiology | 2013 | 13 Pages |
Abstract
Bacteria are often exposed to a hostile environment and have developed a plethora of cellular processes in order to survive. A burgeoning list of small non-coding RNAs (sRNAs) has been identified and reported to orchestrate crucial stress responses in bacteria. Among them, cis-encoded sRNA, trans-encoded sRNA, and 5â²-untranslated regions (UTRs) of the protein coding sequence are influential in the bacterial response to environmental cues, such as fluctuation of temperature and pH as well as other stress conditions. This review summarizes the role of bacterial sRNAs in modulating selected stress conditions and highlights the alliance between stress response and clustered regularly interspaced short palindromic repeats (CRISPR) in bacterial defense.
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Authors
Chee-Hock Hoe, Carsten A. Raabe, Timofey S. Rozhdestvensky, Thean-Hock Tang,