Article ID Journal Published Year Pages File Type
8389219 Meta Gene 2018 13 Pages PDF
Abstract
The present study aims to investigate the role of Global DNA Methylation in Depression. A total of 368 individuals (118 males and 250 females) were screened for depression using PHQ9 (Patient Health Questionnaire 9) and 5-mc% (5-methyl cytosine) content of Peripheral Leucocytes DNA was measured by enzyme linked calorimetric based MethyFlash™ methylated DNA quantification kit. Among individuals with depression a lower Global DNA methylation (though not significant) in terms of 5-mc% (5-methyl cytosine) content was observed compared to individuals without depression.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry, Genetics and Molecular Biology (General)
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