Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8389219 | Meta Gene | 2018 | 13 Pages |
Abstract
The present study aims to investigate the role of Global DNA Methylation in Depression. A total of 368 individuals (118 males and 250 females) were screened for depression using PHQ9 (Patient Health Questionnaire 9) and 5-mc% (5-methyl cytosine) content of Peripheral Leucocytes DNA was measured by enzyme linked calorimetric based MethyFlash⢠methylated DNA quantification kit. Among individuals with depression a lower Global DNA methylation (though not significant) in terms of 5-mc% (5-methyl cytosine) content was observed compared to individuals without depression.
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Authors
Suchita Rawat, Gurjinder Kaur, Suniti Yadav, Maroof Ahmad Khan, Kallur Nava Saraswathy,