Article ID Journal Published Year Pages File Type
839132 Nonlinear Analysis: Real World Applications 2007 24 Pages PDF
Abstract

We discuss the differential equations derived from the Michaelis–Menten model of an enzyme-catalyzed reaction, with no a priori conditions on parameters or initial concentrations. Using an elementary approach, we derive and investigate inequalities and conditions for the validity of the quasi-stationary approximation, confirming results by Segel and Slemrod, and determine new estimates for the pre-steady state period.

Related Topics
Physical Sciences and Engineering Engineering Engineering (General)
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