Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8394354 | Toxicon | 2018 | 7 Pages |
Abstract
We review here the clinical trials on BoNTs performed since 2014 and put them into perspective. We also review the ongoing trials listed by the National Institutes of Health registry (Clinicaltrials.gov). The following indications are reviewed here: blepharospasm, cervical dystonia, spasticity, cerebral palsy, urinary incontinence, headache, topical formulations, postoperative cardiac arrhythmia, keloids and scars. For each of these indications the latest trials are reviewed and commented.
Keywords
TGF-β1pdgfaMMP-1BoNTTeNTCGRPVIPIL-6Investigator's Global AssessmentIgAinterleukin 6transforming growth factor beta 1tetanus neurotoxincervical dystoniabotulinum toxinsadverse eventVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)cerebral palsyMatrix metalloproteinase-1Botulinum neurotoxincalcitonin gene-related peptideClinical trial
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Authors
Antoniangela Cocco, Alberto Albanese,