| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8396897 | Toxicon | 2013 | 21 Pages |
Abstract
Four hundred and fifty micrograms of the venom can be neutralized by 4.2, 18 and 291Â mg of monovalent, polyvalent and anti-idiotype antivenom, respectively. The ELISA results revealed that idiotypic antigens were six times more immunogenic than anti-idiotypes. The anti-idiotype antivenom can be produced on a large scale with minimum venom consumption. In addition, they are non-toxicant in immunized animals and can be used as a vaccine in people at the risk of scorpion stings.
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Authors
M. Khoobdel, B. Nayeri Fasaei, T. Zahraei Salehi, M. Khosravi, M. Taheri, A. Koochakzadeh, B. Masihipour, M.H. Motedayen, S. Akbari,