Article ID Journal Published Year Pages File Type
8397753 Toxicon 2013 7 Pages PDF
Abstract
► The use of antibodies as antitoxins against infectious and venomous agents developed over a century ago. ► War, the Great Depression, and international politics all influenced the course of antivenom development. ► In Arizona lack of antivenom resulted in smuggling and research, conducted by passionate individuals who ignored US FDA requirements. ► Formal clinical trials and US marketing approval of scorpion antivenom occurred 107 years after the first human testing of the concept. ► Commercial success of antivenom appears to depend more on social, economic and political factors than on potency, specificity, and purity.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry, Genetics and Molecular Biology (General)
Authors
,