Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8397910 | Toxicon | 2013 | 10 Pages |
Abstract
⺠Recombinant Helicobacter pylori (rHPU) urease induces paw edema with neutrophil infiltration. ⺠rHPU is chemotactic to human neutrophils independently of its enzyme activity. ⺠rHPU promotes ROS release and inhibits apoptosis of human neutrophils. ⺠Lipoxygenase metabolite(s) mediate the pro-inflammatory effects of rHPU.
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Authors
Augusto F. Uberti, Deiber Olivera-Severo, German E. Wassermann, Adriele Scopel-Guerra, João A. Moraes, Pedro Barcellos-de-Souza, Christina Barja-Fidalgo, Célia. R. Carlini,