Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8397959 | Toxicon | 2013 | 9 Pages |
Abstract
⺠An important step of the complex neurodegenerative process induced by two animal toxins is described. ⺠Primary neuronal cultures, Western blotting and live-imaging approaches were used. ⺠We found here that calpains play a major role in toxins-induced degeneration. ⺠Toxins-induced calpain activation leads to cytoskeleton degradation.
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Authors
Elisa Duregotti, Erik Tedesco, Cesare Montecucco, Michela Rigoni,