| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8398187 | Toxicon | 2013 | 13 Pages |
Abstract
⺠On-line nano-liquid chromatography venom profiling with split to mass spectrometry. ⺠Typical venom amount needed for one analysis of around 2 h was <5 μg. ⺠Dendroaspis jamesoni venom analysis yielded 8 novel AChBP ligands. ⺠Naja annulifera venom analysis yielded 2 novel AChBP ligands. ⺠Naja nivea venom analysis yielded 4 novel AChBP ligands.
Keywords
α7-nicotinic acetylcholine receptorα-NeurotoxinsPLA2sLymnaea stagnalisEICsVenomicsα7-nAChRAChBPUniProtTICCTXα-bungarotoxinmAChRsESIHRSTFAEDATrifluoroacetic acidEffect-directed analysisThree-finger toxinsLOD یا Limit of detectioni.d.Mass spectrometryphospholipases A2Internal Diameterlimit of detectionacetylcholine binding proteinCardiotoxinliquid chromatographyextracted ion chromatogramstotal ion chromatogramnicotinic acetylcholine receptorMuscarinic receptorselectrospray ionization
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Authors
Ferry Heus, Freek Vonk, Reka A. Otvos, Ben Bruyneel, August B. Smit, Henk Lingeman, Michael Richardson, Wilfried M.A. Niessen, Jeroen Kool,