| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8398221 | Toxicon | 2012 | 8 Pages |
Abstract
⺠TLR4-deficient and control mice had similar acute tissue damage after intramuscular injection with Bothrops jararacussu venom. ⺠TLR4-deficient mice had persistent inflammation, increased MMP9 activity and collagen deposition. âºÂ Lack of TLR signaling delayed resolution of muscular injury. ⺠TLR4 signaling exerts a protective role in the muscular injury induced by B. jararacussu venom.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry, Genetics and Molecular Biology (General)
Authors
Eustaquio Luiz Paiva-Oliveira, Rafael Ferreira da Silva, Paulo EmÃlio Correa Leite, José Carlos Cogo, Thereza Quirico-Santos, Jussara Lagrota-Candido,