| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8398392 | Toxicon | 2011 | 13 Pages |
Abstract
⺠Novel protein of biological relevance was isolated from the Vipera ammodytes venom. ⺠Biochemical characterisation identified it as Zn2+-dependent metalloproteinase. ⺠Results allowed its classification into P-IIIc group with only very few members identified so far. âºThe mechanisms underlying the protein's observed hemorrhagic activity were investigated. ⺠Selective proteolytic degradation of basal membrane components and blood clotting factors was found crucial.
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Authors
Tihana KurtoviÄ, Marija Brgles, Adrijana Leonardi, Maja Lang Balija, Igor Križaj, Günter Allmaier, Martina Marchetti-Deschmann, Beata Halassy,