Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8398429 | Toxicon | 2011 | 8 Pages |
Abstract
⺠Cytotoxic and antioxidant protein (NN-32) purified from Indian Naja naja venom. ⺠N-terminal sequence is LKCNKLVPLF and mass is 6.7 kDa. ⺠It was cytotoxic to EAC cells; reduced tumor volume and weight. ⺠NN-32 increased proapoptotic protein caspase 3 and 9 activity and Bax-Bcl2 ratio. ⺠NN-32 increased the antioxidant markers, serum IL-10, decreased murine KC level.
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Authors
Tanaya Das, Shamik Bhattacharya, Babli Halder, Archita Biswas, Shubho Das Gupta, Antony Gomes, Aparna Gomes,