Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8398944 | Mitochondrion | 2016 | 37 Pages |
Abstract
Though the use of these techniques generated great concern about heteroplasmy observation in humans, it seems that with study on these suggested methods there is real hope for effective treatments of old oocyte or oocytes containing mitochondrial problems in the near future.
Keywords
MRTSCNTHmgPMSGCoQ10micromanipulationmitochondrial replacement therapyTFAMAAVnDNAFDAMMPMitochondrial DNANuclear DNAROSSomatic cell nuclear transferoocytemtDNAFood and Drug Administrationendoplasmic reticulummitochondrial transcription factor AMitochondrial activitymetaphase IIpolymerase chain reactionPCRgerminal vesicleMitochondrial membrane potentialCoenzyme Q10high mobility group Reactive oxygen species
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Authors
Sara Darbandi, Mahsa Darbandi, Hamid Reza Khorram khorshid, Mohammad Reza Sadeghi, Safaa Al-Hasani, Ashok Agarwal, Abolfazl Shirazi, Mahnaz Heidari, Mohammad Mehdi Akhondi,