Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8399447 | Mitochondrion | 2014 | 7 Pages |
Abstract
We demonstrate for the first time low myocardial CoQ10 in cardiomyopathy in PA, highlighting secondary mitochondrial impairment as a relevant causative mechanism. According to these findings, a high-dose CoQ10 supplementation could be a potential adjuvant therapeutic to be considered in PA-related cardiomyopathy.
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Authors
J. Baruteau, I. Hargreaves, S. Krywawych, A. Chalasani, J.M. Land, J.E. Davison, M.K. Kwok, G. Christov, A. Karimova, M. Ashworth, G. Anderson, H. Prunty, S. Rahman, S. Grünewald,