| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8399536 | Mitochondrion | 2014 | 6 Pages |
Abstract
The proposed mitochondrial uncoupling mechanism derived from the mtDNA haplogroups J and T could be behind their protective role against OA. The different association found in Spain and the UK could reflect the adaptation of the mtDNA haplogroups to different climatic patterns. The genetic composition of the haplogroup J between the UK and Spain seems to be slightly different, being the m.3394t>c SNP one of the differentially expressed haplogroup J-related polymorphisms.
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Authors
A. Soto-Hermida, M. Fernández-Moreno, N. Oreiro, C. Fernández-López, I. Rego-Pérez, F.J. Blanco,