Article ID Journal Published Year Pages File Type
839959 Nonlinear Analysis: Theory, Methods & Applications 2014 18 Pages PDF
Abstract

The present paper is concerned with a nonlinear initial–boundary value problem derived from a model introduced by Rotenberg (1983) describing the growth of a cell population. Each cell of this population is distinguished by two parameters: its degree of maturity μμ and its maturation velocity vv. At mitosis, the daughter cells and mother cells are related by a general reproduction rule. We prove existence and uniqueness results in the case where the total cross-section and the boundary conditions are depending on the total density of population. Local and nonlocal reproduction rules are discussed.

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