Article ID Journal Published Year Pages File Type
8400848 Progress in Biophysics and Molecular Biology 2016 17 Pages PDF
Abstract
The Dynamic Clamp approach, applied to the If study in cardiomyocytes for the first time and rate-adapted to manage intercellular variability, indicated that: i) the quantitative description of the If current in the Severi-DiFrancesco model accurately reproduces the effects of the real current on rabbit sinoatrial cell pacemaking rate and ii) a significant portion (50-60%) of the physiological autonomic rate modulation is due to the shift of the If activation curve.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biophysics
Authors
, , , , , , ,