| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8402096 | Advanced Drug Delivery Reviews | 2018 | 100 Pages |
Abstract
A schematic drawing of the different phases of tendon healing, including tendon appearance, molecular changes, growth factors involved and the time course. Tendon healing can be subdivided into three different stages: the inflammation phase, the reparation phase and the remodeling phase. Various growth factors are involved in the healing phases in a distinct time-specific pattern. They tightly regulate cell migration, proliferation and ECM production and organization.353
Keywords
HB-EGFbFGFMSCCTGFGDFECMPrPinfPDGFETMIGF-1Biglycanperivascular cellCOMPadipose tissue derived mesenchymal stem cellsGNTfmodBGNgrowth and differentiation factorsGFPMMPSMCDCNscxScleraxisElastinMRIinsulin-like growth factor-1interferoninterleukinMagnetic resonance imagingSMAdecorinMesenchymal stem cellsbone marrow derived mesenchymal stem cellsConnective tissue growth factorplatelet-derived growth factorbasic fibroblast growth factorFibromodulinFibronectinlumLumicanExtracellular matrixmatrix metalloproteinaseBMPbone marrowNitric oxidegreen fluorescent proteinCartilage oligomeric matrix proteinBone morphogenetic proteinPlatelet rich plasmapolyethylene glycolPEGCollagencolGlyceryl trinitrate
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Authors
Magdalena Schneider, Peter Angele, Tero A.H. Järvinen, Denitsa Docheva,