| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8403205 | Advanced Drug Delivery Reviews | 2015 | 29 Pages |
Abstract
Different types of scaffolds (porous matrix, nano-fiber mesh, hydrogels and microspheres) are used to deliver bioactive molecules. This can be combined with a number of physicomechanical strategies to enhance treatment of various bone tissue defects and diseases.207
Keywords
HIF-1αRGDBMSCsCOX-2RUNX2ECMSDF-1MSCPGE2BMP-2GAGPDGFPGFc-di-GMPArg-Gly-AspOsteoinductiveTNFTGF-βLPSIGFIL-1MAPK/ERKROSOsteoconductiveMRSAGene deliveryinterleukin 1Bone regenerationTransforming Growth Factor BetaCell deliveryDrug deliveryBiomimetic scaffoldsChemical vapor depositionCVDbone marrow stromal cellscyclooxygenase 2placenta growth factorRunt-related transcription factor 2Growth factorsVascular Endothelial Growth Factor (VEGF)platelet-derived growth factorInsulin-like growth factortumor necrosis factorCalcium phosphateExtracellular matrixHydroxyapatitehypoxia-inducible factor-1 alphaProteoglycanBone morphogenetic protein-2Prostaglandin E2CaPGlycosaminoglycanReactive oxygen species
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Authors
Marc A. Fernandez-Yague, Sunny Akogwu Abbah, Laoise McNamara, Dimitrios I. Zeugolis, Abhay Pandit, Manus J. Biggs,