Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8408206 | Computational and Structural Biotechnology Journal | 2018 | 5 Pages |
Abstract
Epigenetic modifications are hereditable and modifiable factors that do not alter the DNA sequence. These epigenetic factors include DNA methylation, acetylation of histones and non-coding RNAs. Epigenetic factors have mainly been associated with cancer but also with other diseases and conditions such as diabetes or obesity. In addition, epigenetic modifications could play an important role in cardiovascular diseases, including stroke. We review the latest advances in stroke epigenetics, focusing on DNA methylation studies and the future perspectives in this field.
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Authors
Jerzy Krupinski, Caty Carrera, Elena MuiƱo, Nuria Torres, Raid Al-Baradie, Natalia Cullell, Israel Fernandez-Cadenas,