| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8410400 | Drug Discovery Today | 2013 | 15 Pages |
Abstract
- We describe a practical drug discovery project for undergraduates.
- The project aims to mimic real-life drug discovery.
- Students design and make target compounds in teams.
- The focus is to balance potency, lipophilicity and solubility.
- We extend the published structure-activity relationships of PI3Kδ inhibitors.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biotechnology
Authors
M. Jonathan Fray, Simon J.F. Macdonald, Ian R. Baldwin, Nick Barton, Jack Brown, Ian B. Campbell, Ian Churcher, Diane M. Coe, Anthony W.J. Cooper, Andrew P. Craven, Gail Fisher, Graham G.A. Inglis, Henry A. Kelly, John Liddle, Aoife C. Maxwell,