| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8410510 | Drug Discovery Today | 2013 | 7 Pages |
Abstract
⺠Neuregulin (NRG)-1 regulates myocardial function. ⺠NRG-1 regulates vascular function. ⺠Disabled NRG-1/ErbB signaling is implicated in the progression of heart failure. ⺠Animal studies showed the therapeutic effects of NRG-1 in heart failure. ⺠Clinical trials showed therapeutic potential of recombinant human NRG-1 in heart failure.
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Authors
Pedro Mendes-Ferreira, Gilles W. De Keulenaer, Adelino F. Leite-Moreira, Carmen Brás-Silva,