| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8410583 | Drug Discovery Today | 2013 | 8 Pages |
Abstract
⺠The AhR is a transcription factor activated by diverse exogenous compounds. ⺠The AhR regulates the expression of xenobiotic metabolism genes. ⺠KO models have revealed that the AhR also regulates endogenous processes. ⺠AhR modulators might be used as anti-tumorigenic or anti-inflammatory drugs. ⺠The AhR also regulates the proliferation of hematopoietic stem cells.
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Authors
Erwan Guyot, Aline Chevallier, Robert Barouki, Xavier Coumoul,