| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8410671 | Drug Discovery Today | 2013 | 8 Pages |
Abstract
⺠Can every biological state be represented by a given gene expression signature? ⺠Recently, signatures have been used as proxies of clinicopathological phenotypes. ⺠Drug-drug/drug-disease 'connections' have been inferred by signature matching. ⺠This allowed the prediction of new application for already approved drugs. ⺠A massive amount of public transcriptional data is ready to be exploited in this way.
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Authors
Francesco Iorio, Timothy Rittman, Hong Ge, Michael Menden, Julio Saez-Rodriguez,