| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8410736 | Drug Discovery Today | 2013 | 7 Pages |
Abstract
⺠Details the potential of developing the spliceosome as an anticancer target. ⺠Reviews currently available natural product and synthetic spliceosome modulators. ⺠Discusses the role of alternative splicing in cancer therapy. ⺠Reviews the selective antitumor activity of spliceosomal targeting agents. ⺠Elucidates potential mechanisms of cytotoxicity induced by spliceosome modulators.
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Authors
Thomas R. Webb, Amanda S. Joyner, Philip M. Potter,