Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8410885 | Drug Discovery Today | 2009 | 9 Pages |
Abstract
This review illustrates notable recent progress in the field of medicinal bioinorganic chemistry as many new approaches to the design of innovative metal-based anticancer drugs are emerging. Current research addressing the problems associated with platinum drugs has focused on other metal-based therapeutics that have different modes of action and on prodrug and targeting strategies in an effort to diminish the side-effects of cisplatin chemotherapy.
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Authors
Sabine H. van Rijt, Peter J. Sadler,