| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8411081 | Drug Discovery Today: Disease Models | 2016 | 6 Pages |
Abstract
Despite significant computational challenges, a number of tools have been developed recently to leverage the mouse to model human disease. Here we review these tools and show how they can be applied in the identification of candidate genes and therapeutic targets as well as mouse models for mechanistic studies and drug validation.
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Authors
Melissa Haendel, Irene Papatheodorou, Anika Oellrich, Christopher J. Mungall, Nicole Washington, Suzanna E. Lewis, Peter N. Robinson, Damian Smedley,