| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8411954 | European Journal of Pharmaceutics and Biopharmaceutics | 2018 | 24 Pages |
Keywords
DMFμwEchinoderm microtubule-associated protein-like 4EML4Thieno[3,2-d]pyrimidineFDAEML4-ALK fusionGatekeeper mutationcMETPDBc-MetN,N-dimethylformamideN,N-diisopropylethylamineALKSolubilityScaffold hoppingGatekeeperRoom temperatureFood and Drug AdministrationNSCLCNon-small cell lung cancerAnaplastic lymphoma kinaseProtein kinase inhibitorDIPEAwild typeProtein Data BankPurineTEAhepatocyte growth factor receptor
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Authors
Laura Schlütke, Markus Immer, Lutz Preu, Frank Totzke, Christoph Schächtele, Michael H.G. Kubbutat, Conrad Kunick,