Calendering as a direct shaping tool for the continuous production of fixed-dose combination products via co-extrusion

Article ID	Journal	Published Year	Pages	File Type
8412909	European Journal of Pharmaceutics and Biopharmaceutics	2015	7 Pages	PDF

Keywords

FDC Dibutyl sebacate USP MDSC RCS MPT HCT DBS TPI ROI HME Immediate release Sustained release Ethylcellulose Ultraviolet Hot-melt extrusion Co-extrusion Polyethylene oxide United States Pharmacopeia bitmap Fixed-dose combination Terahertz pulsed imaging Calendering Continuous production Micro-computed tomography glass transition temperature Metoprolol tartrate BMP region of interest Micro-CT Hydrochlorothiazide Molecular weight XRD X-ray diffraction polyethylene glycol PEG PEO Modulated differential scanning calorimetry

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biotechnology

Calendering as a direct shaping tool for the continuous production of fixed-dose combination products via co-extrusion

Authors

A.-K. Vynckier, H. Lin, J.A. Zeitler, J.-F. Willart, E. Bongaers, J. Voorspoels, J.P. Remon, C. Vervaet,